Article
Biofilm dispersal cells of a cystic fibrosis Pseudomonas aeruginosa isolate exhibit variability in functional traits likely to contribute to persistent infection.
FEMS immunology and medical microbiology - 1 Nov 2012
Woo Jerry K K, Webb Jeremy S, Kirov Sylvia M, Kjelleberg Staffan, Rice Scott A
Abstract excerpt
Persistent lung infection by Pseudomonas aeruginosa is typically associated with the development of biofilms, the appearance of morphotypic variants and reduction in the expression of acute virulence factors. We have characterised and compared functional traits [carbon substrate utilisation, attachment and biofilm formation, protease and elastase activity, quorum-sensing (QS)] of the biofilm dispersal populations...
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