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Article

Newer insights into the pathogenesis of experimental autoimmune thyroiditis.

International reviews of immunology - 1 Jan 2000

Stafford E A, Rose N R

Abstract excerpt

Experimental autoimmune thyroiditis (EAT), produced in the mouse by immunization with murine thyroglobulin plus complete Freund's adjuvant, represents a valuable model for studying the pathogenesis of human chronic (Hashimoto's) thyroiditis. A major issue requiring clarification is the difference between benign autoimmunity, characterized solely by production of autoantibodies to thyroglobulin, and pathogenic...

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PMID: 11129113
DOI: 10.3109/08830180009088510

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