NMDA-sensitive L-[3H]glutamate binding in cerebral cortex of El mice.

doi:10.1016/0920-1211(90)90075-7

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Article

NMDA-sensitive L-[3H]glutamate binding in cerebral cortex of El mice.

Epilepsy research - 1 Aug 1990

Oguro K, Ito M, Tsuda H, Mutoh K, Shiraishi H, Shirasaka Y, Mikawa H

Abstract excerpt

NMDA-sensitive L-[3H]glutamate binding was examined in the brains of El mice, a genetic animal model of epilepsy, and in ddY mice. In whole brain, Scatchard analysis showed that both stimulated and unstimulated El mice had significantly lower Bmax values for binding than did ddY mice. In regional...

Topics

Animals
Cerebral Cortex
Disease Models, Animal
Disease Susceptibility
Epilepsy
Genetic Predisposition to Disease
Glutamates
Membranes
Mice
Mice, Inbred Strains
N-Methylaspartate
Receptors, N-Methyl-D-Aspartate
Tritium

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