Article
GABA and opioid binding distribution in the brain of the seizure-resistant Proechimys guyannensis: an autoradiography study.
Synapse (New York, N.Y.) - 1 Oct 2006
Rocha Luisa, Arida Ricardo Mario, Carvalho Reinaldo De Amorim, Scorza Fulvio Alexandre, Neri-Bazan Leticia, Cavalheiro Esper Abrao
Abstract excerpt
Proechimys guyannensis rodents present resistance to epilepsy. Autoradiography was used to map GABA(A) ((3)H-Muscimol), benzodiazepine ((3)H-Flunitrazepam), mu ((3)H-DAMGO), and delta ((3)H-DPDPE) opioid receptor binding in adult Proechimys guyannensis brain under normal conditions. Results were compared with values obtained from adult Wistar rats. Proechimys presented reduced (3)H-Muscimol binding in several...
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