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Article

Extensive effects of in vitro oocyte maturation on rhesus monkey cumulus cell transcriptome

13 Apr 2011

Abstract excerpt

The elaboration of a quality oocyte is integrally linked to the correct developmental progression of cumulus cell phenotype. In humans and nonhuman primates, oocyte quality is diminished with in vitro maturation. To determine the changes in gene expression in rhesus monkey cumulus cells (CC) that occur during the final day prior to oocyte maturation and how these changes differ between in vitro (IVM) and in vivo...

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PMID: 21487073
DOI: 10.1152/ajpendo.00686.2010

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