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Article

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules.

PloS one - 1 Apr 2011

Hultberg Anna, Temperton Nigel J, Rosseels Valérie, Koenders Mireille, Gonzalez-Pajuelo Maria, Schepens Bert, Ibañez Lorena Itatí, Vanlandschoot Peter, Schillemans Joris, Saunders Michael, Weiss Robin A, Saelens Xavier, Melero José A, Verrips C Theo, Van Gucht Steven, de Haard Hans J

Abstract excerpt

For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (Fusion protein), Rabies virus (Glycoprotei...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Dose-Response Relationship, Immunologic

Share to Influenza A Virus, H5N1 Subtype

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Source

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Identifiers

PMID: 21483777
DOI: 10.1371/journal.pone.0017665
PMCID: PMC3069976

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21483777-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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