Article
Reconciliation of genome-scale metabolic reconstructions for comparative systems analysis.
PLoS computational biology - 1 Mar 2011
Oberhardt Matthew A, Puchałka Jacek, Martins dos Santos Vítor A P, Papin Jason A
Abstract excerpt
In the past decade, over 50 genome-scale metabolic reconstructions have been built for a variety of single- and multi- cellular organisms. These reconstructions have enabled a host of computational methods to be leveraged for systems-analysis of metabolism, leading to greater understanding of observed phenotypes. These methods have been sparsely applied to comparisons between multiple organisms, however, due...
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