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Article

IDH1 mutation, a genetic alteration associated with adult gliomatosis cerebri.

Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Feb 2012

Narasimhaiah Deepti, Miquel Catherine, Verhamme Elisabeth, Desclée Paul, Cosnard Guy, Godfraind Catherine

Abstract excerpt

Recently, mutations in IDH1 and IDH2 have been reported as an early and common genetic alteration in diffuse gliomas, being possibly followed by 1p/19q loss in oligodendrogliomas and TP53 mutations in astrocytomas. Lately, IDH1 mutations have also been identified in adult gliomatosis cerebri (GC). The aim of our study was to test the status of IDH1/2, p53 and of chromosomes 1 and 19 in a series of 12 adult and...

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Source

Identifiers

PMID: 21481010
DOI: 10.1111/j.1440-1789.2011.01216.x

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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IDH1 mutation, a genetic alteration associated with adult gliomatosis cerebri.PMID 21481010Read ↗

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