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Article

Deletion of SNAP-23 results in pre-implantation embryonic lethality in mice.

PloS one - 29 Mar 2011

Suh Young Ho, Yoshimoto-Furusawa Aki, Weih Karis A, Tessarollo Lino, Roche Katherine W, Mackem Susan, Roche Paul A

Abstract excerpt

SNARE-mediated membrane fusion is a pivotal event for a wide-variety of biological processes. SNAP-25, a neuron-specific SNARE protein, has been well-characterized and mouse embryos lacking Snap25 are viable. However, the phenotype of mice lacking SNAP-23, the ubiquitously expressed SNAP-25 homolog, remains unknown. To reveal the importance of SNAP-23 function in mouse development, we generated Snap23-null mice...

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Source

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Identifiers

PMID: 21479242
DOI: 10.1371/journal.pone.0018444
PMCID: PMC3066230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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