Insertion/deletion polymorphism of angiotensin I-converting enzyme gene is linked with chromophobe renal cell carcinoma.

doi:10.1016/j.urology.2010.11.033

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Article

Insertion/deletion polymorphism of angiotensin I-converting enzyme gene is linked with chromophobe renal cell carcinoma.

Urology - 1 Apr 2011

de Martino Michela, Klatte Tobias, Schatzl Georg, Waldert Matthias, Remzi Mesut, Haitel Andrea, Kramer Gero, Marberger Michael

Abstract excerpt

OBJECTIVES: To study the putative significance of angiotensin I-converting enzyme (ACE) in renal cell carcinoma (RCC). Recent evidence has suggested that a 287-base pair insertion (I)/deletion (D) polymorphism (rs4646994) of the angiotensin I-converting enzyme (ACE) might be associated with cancer risk and progression. METHODS: The present case-control study accrued 383 subjects, including 210 with RCC and 173...

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PMID: 21477733
DOI: 10.1016/j.urology.2010.11.033

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