Article
The association between ACE polymorphism and risk of colorectal cancer in a Chinese population.
Clinical biochemistry - 1 Oct 2011
Liu Song-Yan, Sima Xiutian, Wang Chun-Hui, Gao Ming
Abstract excerpt
OBJECTIVES: Angiotensin I-converting enzyme (ACE) plays crucial roles not only in the regulation of circulatory homeostasis but also in the pathology of carcinomas. An insertion-deletion (I/D) polymorphism in intron 16 of ACE gene was identified to be functional. We aimed to investigate the association between ACE I/D polymorphism and risk of colorectal cancer (CRC). DESIGN AND METHODS: Using genomic DNA from 241...
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