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Article

Renin-angiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/deletion polymorphism, and cancer: the Rotterdam Study.

Cancer - 15 Feb 2008

van der Knaap Ronald, Siemes Claire, Coebergh Jan-Willem W, van Duijn Cornelia M, Hofman Albert, Stricker Bruno H Ch

Abstract excerpt

BACKGROUND: Angiotensin I-converting enzyme (ACE) inhibitors, angiotensin II antagonists, and the ACE insertion/deletion (I/D) gene polymorphism all influence serum angiotensin II action. Because angiotensin II levels have been associated with cancer, the objective of the current epidemiologic study was to investigate whether renin-angiotensin system inhibitors and/or ACE genotypes were associated with an altered...

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Source

Identifiers

PMID: 18181094
DOI: 10.1002/cncr.23215

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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