Article
Association of a common genetic variant (insertion/deletion) in ACE gene with prostate cancer susceptibility in a Tunisian population.
Journal of clinical laboratory analysis - 1 Jan 2022
Said Rahma, Jenni Rim, Boussetta Sami, Ammous Feryel, Zouari Skander, Zaghbib Selim, Chakroun Marouene, Derouiche Amine, Chebil Mohamed, Ouerhani Slah
Abstract excerpt
BACKGROUND: Angiotensin-converting enzyme (ACE) plays a pivotal role in several pathologies including cancers. The association of insertion/deletion (I/D) polymorphism of the ACE gene with prostate cancer (PC) risk remains controversial. We aimed to investigate for the first time, to our Knowledge, in North Africa the potential relationship between ACE I/D polymorphism with PC susceptibility and clinical outcomes...
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