Article
Polymorphism of neurodegeneration-related genes associated with Parkinson's disease risk.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Sept 2022
Li Jiaxin, Yi Minhan, Li Binbin, Yin Shujuan, Zhang Ying, Huang Zini, Shu Li, Zhang Yuan
Abstract excerpt
BACKGROUND: Neurodegenerative genes are critical in neuronal loss in Parkinson's disease (PD). We performed a systematic meta-analysis including all the studies published on PD risk related to genes encoding enzymes vital for dopamine metabolism and neuron survival. METHODS: We included neurodegeneration-related genes which were divided into four groups according to their functions: main enzymes in dopamine...
Topics
- Alleles
- Dopamine
- Genetic Predisposition to Disease
- Humans
- Parkinson Disease
- Polymorphism, Single Nucleotide
