Article
Osteopontin polymorphic susceptibility factor for Parkinson's disease among patients with Gaucher disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Jun 2011
Ribner Avigayil, Altarescu Gheona, Zimran Ari, Elstein Deborah
Abstract excerpt
BACKGROUND: There is an increased incidence of Parkinson's disease among obligate carriers of the common glucocerebrosidase mutations, and among patients with Parkinson disease there is an increased number who are carriers of glucocerebrosidase mutations. A Gaucher mutation is considered a susceptibility factor for Parkinson's disease. Osteopontin single-nucleotide polymorphism-66 is associated with Lewy body...
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