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Article

Differentially expressed genes in Men1 knockout and wild‑type embryoid bodies for pancreatic islet development.

Molecular medicine reports - 1 Jan 2000

Zhang Hong-Li, Li Wen-Yi, Zhang Cui-Ping, Zhu Ya-Xin, Wu Ling, Long Hong-Mei, Li Guo, Luo Min

Abstract excerpt

The Men1 gene has been identified as the gene responsible for MEN-1, a hereditary syndrome transmitted as an autosomal dominant trait. Disruption of the Men1 gene results in defects in the development of multiple organs, including pancreatic islets. Homozygous disruption of Men1 in mice causes embryonic lethality, making it difficult to determine the genes involved in defects of pancreatic islets during embryonic...

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Share to Embryoid Bodies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Islets of Langerhans

Share to Microscopy, Phase-Contrast

Share to Oligonucleotide Array Sequence Analysis

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Source

Identifiers

PMID: 21468568
DOI: 10.3892/mmr.2011.409

Genes

FOXA2
SOX17
SOX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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