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Trisomic pregnancy and elevated FSH: implications for the oocyte pool hypothesis

5 Apr 2011

Abstract excerpt

BACKGROUND: Some studies, but not all, support the hypothesis that trisomy frequency is related to the size of the oocyte pool, with the risk increased for women with fewer oocytes (older ovarian age). We tested this hypothesis by comparing hormonal indicators of ovarian age among women who had trisomic pregnancy losses with indicators among women with non-trisomic losses or chromosomally normal births. The three...

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PMID: 21467203
DOI: 10.1093/humrep/der091

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