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Antral follicle count as a marker of ovarian biological age to reflect the background risk of fetal aneuploidy

27 Mar 2014

Abstract excerpt

STUDY QUESTION: Can antral follicle count (AFC) measured during pregnancy be used as a marker of ovarian age to assess the background risk of fetal aneuploidy? SUMMARY ANSWER: AFC was lower than expected according to maternal chronological age in trisomic pregnancies; therefore ovarian age could potentially reflect a more precise background risk of fetal aneuploidy screening. WHAT IS KNOWN ALREADY: The decline in...

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PMID: 24682614
DOI: 10.1093/humrep/deu055

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