Article
β1- and β2-integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation
18 Dec 2020
Abstract excerpt
The integrin family, an indispensable part of cell-cell and cell-matrix interactions, consists of a group of heterodimeric adhesion receptors formed by α- and β-integrin subunits. Their wide expression and unique bidirectional signaling pathways allow them to play roles in a variety of biological activities including blood clot formation, cell attachment, and migration. Evidence suggests that integrins are...
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