Article
Effect of chronic high altitude hypoxia on foetal and maternal juxta-alveolar distal pulmonary smooth muscle cells actin and calponin organisation and growth profiles.
West African journal of medicine - 1 Jan 2000
John T A
Abstract excerpt
BACKGROUND: The effect of chronic high altitude hypoxia (CHAH) in the juxta-alveolar region near the air-blood interface is unknown because of the experimental inaccessibility of this region. OBJECTIVE: To examine primary cultures of digested juxta-alveolar smooth muscle cells for hypoxia-induced changes. METHODS: Smooth Muscle Cells (SMCs) obtained by dispase digestion of the extreme lung parenchyma were used to...
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