Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of stable pluripotent stem cells from NOD mouse tail-tip fibroblasts.

Diabetes - 1 May 2011

Liu Jun, Ashton Michelle P, Sumer Huseyin, O'Bryan Moira K, Brodnicki Thomas C, Verma Paul J

Abstract excerpt

OBJECTIVE: The NOD mouse strain has been widely used to investigate the pathology and genetic susceptibility for type 1 diabetes. Induced pluripotent stem cells (iPSCs) derived from this unique mouse strain would enable new strategies for investigating type 1 diabetes pathogenesis and potential therapeutic targets. The objective of this study was to determine whether somatic fibroblasts from NOD mice could be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibroblasts
Share to Flow Cytometry
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Induced Pluripotent Stem Cells

Share to Kruppel-Like Factor 4

Share to Mice, Inbred NOD

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 21464439
DOI: 10.2337/db10-1540
PMCID: PMC3292312

Genes

SOX2
KLF4
NANOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of stable pluripotent stem cells from NOD mouse tail-tip fibroblasts.PMID 21464439Read ↗

Differentiation and Transplantation of Functional Pancreatic Beta Cells Generated from Induced Pluripotent Stem Cells Derived from a Type 1 Diabetes Mouse ModelSemantic proximity Read ↗

Transgene-Free Disease-Specific Induced Pluripotent Stem Cells from Patients with Type 1 and Type 2 DiabetesSemantic proximity Read ↗

Generation of pluripotent stem cells from patients with type 1 diabetesSemantic proximity Read ↗

Male germline and embryonic stem cell lines from NOD mice: efficient derivation of GS cells from a nonpermissive strain for ES cell derivation.Semantic proximity Read ↗

The Derivation of Highly Germline-Competent Embryonic Stem Cells Containing NOD-Derived GenomeSemantic proximity Read ↗

Generation of an induced pluripotent stem cell line (ZZUi020-A) from a patient with Parkinson's disease harboring the intermediate-length GGC repeat expansions in the NOTCH2NLC gene.Semantic proximity Read ↗

From iPSCs to Pancreatic β Cells: Unveiling Molecular Pathways and Enhancements With Vitamin C and Retinoic Acid in Diabetes ResearchSemantic proximity Read ↗

Dual Small-Molecule Targeting of SMAD Signaling Stimulates Human Induced Pluripotent Stem Cells toward Neural LineagesSemantic proximity Read ↗

In vitro-generation of islets in long-term cultures of pluripotent stem cells from adult mouse pancreas.Semantic proximity Read ↗

Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell LinesSemantic proximity Read ↗

Generation of pancreatic progenitors from human pluripotent stem cells by small moleculesSemantic proximity Read ↗

The Efficient Generation of Induced Pluripotent Stem (iPS) Cells from Adult Mouse Adipose Tissue-Derived and Neural Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.