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Article

Effect of the amyloidogenic L75P apolipoprotein A-I variant on HDL subpopulations.

Clinica chimica acta; international journal of clinical chemistry - 11 Jun 2011

Gomaraschi Monica, Obici Laura, Simonelli Sara, Gregorini Gina, Negrinelli Alessandro, Merlini Giampaolo, Franceschini Guido, Calabresi Laura

Abstract excerpt

BACKGROUND: Hereditary amyloidosis due to mutations of apolipoprotein A-I (apoA-I) is a rare disease characterized by the deposition of amyloid fibrils constituted by the N-terminal fragment of apoA-I in several organs. L75P is a variant of apoA-I associated with systemic amyloidosis predominantly involving the liver, kidneys, and testis, identified in a large number of unrelated subjects. Objective of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21458433
DOI: 10.1016/j.cca.2011.03.027
PMCID: PMC3096778

Genes

LCAT

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