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Article

Percutaneous Absorption in Man: In vitro-in vivo Correlation

1 Jan 2011

Abstract excerpt

AIMS: To examine the existing literature to determine the degree to which percutaneous absorption data obtained using the excised human skin model match those obtained from living man. METHODS: The scientific literature was reviewed to collect data on compounds whose percutaneous absorption through human skin had been measured under both in vitro and in vivo conditions. The in vitro-in vivo (IVIV) correlation was...

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PMID: 21455015
DOI: 10.1159/000324884

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