Article
Opsin synthesis and mRNA levels in dystrophic retinas devoid of outer segments in retinal degeneration slow (rds) mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 1990
Agarwal N, Nir I, Papermaster D S
Abstract excerpt
Opsin gene regulation, as a function of outer segment structure, was studied in normal and mutant retinal degeneration slow (rds) mice. We investigated the level of expression of the opsin gene in the rds mutant to determine if the reduced opsin content observed in this mutation (around 3% of nor...
Topics
- Animals
- Cell Nucleus
- DNA Probes
- Eye Proteins
- Gene Expression
- Immunoblotting
- Immunohistochemistry
- Kinetics
- Mice
- Mice, Inbred BALB C
- Mice, Mutant Strains
- Microscopy, Immunoelectron
- Mutation
- Nucleic Acid Hybridization
- Photoreceptor Cells
- RNA, Messenger
- Retinal Degeneration
- Rod Cell Outer Segment