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Article

A nuclear variant of ErbB3 receptor tyrosine kinase regulates ezrin distribution and Schwann cell myelination.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 Mar 2011

Adilakshmi Tadepalli, Ness-Myers Jennifer, Madrid-Aliste Carlos, Fiser Andras, Tapinos Nikos

Abstract excerpt

Reciprocal interactions between glia and neurons are essential for the proper organization and function of the nervous system. Recently, the interaction between ErbB receptors (ErbB2 and ErbB3) on the surface of Schwann cells and neuronal Neuregulin-1 (NRG1) has emerged as the pivotal signal that controls Schwann cell development, association with axons, and myelination. To understand the function of NRG1-ErbB2/3...

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Identifiers

PMID: 21451047
DOI: 10.1523/JNEUROSCI.5635-10.2011
PMCID: PMC3086203

Genes

NRG1
HMGB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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