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Article

A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities

28 Mar 2011

Abstract excerpt

BACKGROUND: The diversity and complexity of the human androgen receptor (AR) splicing variants are well appreciated but not fully understood. The goal of this study is to generate a comprehensive expression signature of AR variants in castration-resistant prostate cancer (CRPC), and to address the relative importance of the individual variants in conferring the castration-resistant phenotype. METHODS: A modified...

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PMID: 21446008
DOI: 10.1002/pros.21382

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