Article
In vitro antiviral activity of arbidol against Chikungunya virus and characteristics of a selected resistant mutant.
Antiviral research - 1 Jun 2011
Delogu Ilenia, Pastorino Boris, Baronti Cécile, Nougairède Antoine, Bonnet Emilie, de Lamballerie Xavier
Abstract excerpt
Arbidol (ARB) is an antiviral drug originally licensed in Russia for use against influenza and other respiratory viral infections. Although a broad-spectrum antiviral activity has been reported for this drug, there is until now no data regarding its effects against alphavirus infection. Here, the in vitro antiviral effect of ARB on Chikungunya virus (CHIKV) replication was investigated and this compound was found...
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