Article
Epidermal growth factor receptor overexpression in malignant pleural mesothelioma: prognostic correlations.
Journal of surgical oncology - 1 Nov 2011
Rena Ottavio, Boldorini Luciano R, Gaudino Erica, Casadio Caterina
Abstract excerpt
BACKGROUND: To evaluate epidermal growth factor receptor (EGFR) phenotypic expression and related gene status in malignant pleural mesothelioma (MPM) and to correlate the results with patients' prognosis. METHOD: Eighty-three cases of MPM specimens were submitted to immunohistochemical (IHC) staining to evaluate the expression of EGFR protein; positive cases were submitted to fluorescence in situ hybridization...
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