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Article

Endothelin-1 polymorphisms involved in impaired exercise tolerance in COPD patients. A pilot study.

European review for medical and pharmacological sciences - 1 Feb 2011

Sampsonas E, Lykouras D, Drakatos P, Moschopoulou A, Spiropoulos K, Karkoulias K

Abstract excerpt

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide that may lead to impaired exercise tolerance. In this study we exhibit the relationship between two endothelin-1 (+134 3A/4A and G198T) SNPs involved in COPD and their association to impaired exercise tolerance. MATERIALS AND METHODS: The study population consisted of 22 COPD smokers and 32 smoking...

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PMID: 21434478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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