Article
'Energy expenditure genes' or 'energy absorption genes': a new target for the treatment of obesity and Type II diabetes.
Future medicinal chemistry - 1 Dec 2010
Braud Sandrine, Ciufolini Marco, Harosh Itzik
Abstract excerpt
Several hundred genes associated or linked to obesity have been described in the scientific literature. Whereas many of these genes are potential targets for the treatment of obesity and associated conditions, none of them have permitted the developement of an efficient drug therapy. As proposed by the 'thrifty genotype' theory, obesity genes may have conferred an evolutionary advantage in times of food shortage...
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