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Article

How obesity causes diabetes: not a tall tale.

Science (New York, N.Y.) - 21 Jan 2005

Lazar Mitchell A

Abstract excerpt

The epidemic of obesity-associated diabetes is a major crisis in modern societies, in which food is plentiful and exercise is optional. The biological basis of this problem has been explored from evolutionary and mechanistic perspectives. Evolutionary theories, focusing on the potential survival advantages of "thrifty" genes that are now maladaptive, are of great interest but are inherently speculative and...

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PMID: 15662001
DOI: 10.1126/science.1104342

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