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Article

Genetic characterization of warfarin sensitivity in a population of cardiovascular patients on chronic anticoagulation.

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology - 1 Dec 2010

Jorge Elisabete, Pêgo João Mariano, Baptista Rui, Lourenço Margarida, Marques Isabel, Correia Ana, Monteiro Pedro, Antunes Ferrer, Providência Luís A

Abstract excerpt

BACKGROUND: Genetic factors account for 35-40% of the interindividual variation observed in response to warfarin. The most important genes involved are CYP2C9 (cytochrome P450 2C9) and VKORC1 (vitamin K epoxide reductase complex subunit 1). OBJECTIVES: To determine the prevalence of the different genotypes influencing response to oral anticoagulants in a population of cardiovascular patients on chronic...

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Source

Identifiers

PMID: 21428138

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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