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Article

Wnt signaling in lip and palate development.

Frontiers of oral biology - 1 Jan 2012

He Fenglei, Chen Yiping

Abstract excerpt

Wnt signaling regulates a variety of cell behaviors and represents a major pathway in development and disease. Mutations in Wnt genes and their downstream targets have been implicated in human craniofacial abnormalities, including the most prevalent birth defect, cleft lip with or without palate. Formation of the upper lip and palate is a complicated process and is composed of a series of highly coordinated steps...

Topics

Cleft Lip
Cleft Palate
Embryonic Development
Humans
Lip
Mutation
Palate
Wnt Signaling Pathway
beta Catenin

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22759672
DOI: 10.1159/000337619

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