Article
Evaluation of prognostic factors and their capacity to predict biological behavior in gastrointestinal stromal tumors.
International journal of surgical pathology - 1 Aug 2011
Calabuig-Fariñas Silvia, López-Guerrero José Antonio, Navarro Samuel, Machado Isidro, Poveda Andrés, Pellín Antonio, Llombart-Bosch Antonio
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are c-KIT-signaling-driven mesenchymal tumors of the human digestive tract, many of which have c-KIT or PDGFRα activating mutations. The authors studied the immunohistochemical markers, c-KIT and PDGFRα mutations, in GISTs and their association with the clinicopathological and clinical follow-up in 145 GISTs. Tumors were located mainly in the stomach, the median tumor size...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.