Article
[To screen, clone and sequence TIGR gene mutation in Chinese patients with primary open- angle glaucoma].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology - 1 Nov 2000
Zhuo Y, Ge J, Guo Y, Lan Y, Li L
Abstract excerpt
OBJECTIVE: To study trabecular meshwork induced glucocorticoid response protein (TIGR) gene mutation in Chinese patients with primary open-angle glaucoma (POAG). METHODS: (1) From 70 patients with POAG and 20 normal controls, TIGR gene which consists of three exons (7 pairs of primer) was amplified by polymerase chain reaction (PCR). The mutation of PCR amplification products was evaluated by single-stranded...
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