Article
A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women.
Carcinogenesis - 1 Jun 2008
Wang Yan, Hu Zhibin, Liang Jie, Wang Zhanwei, Tang Jinhai, Wang Shui, Wang Xuechen, Qin Jianwei, Wang Xinru, Shen Hongbing
Abstract excerpt
Telomerase reactivation, which prevents telomere shortening and maintains cell viability, is crucial for the continued growth or progression of cancer cells. A minisatellite tandem repeat, MNS16A, located in the downstream of the human telomerase reverse transcriptase (hTERT) gene was recently identified and reported to have an effect on hTERT expression and telomerase activity. The aim of this study was to test...
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