Article
MNS16A minisatellite genotypes in relation to risk of glioma and meningioma and to glioblastoma outcome.
International journal of cancer - 15 Aug 2009
Andersson Ulrika, Osterman Pia, Sjöström Sara, Johansen Christoffer, Henriksson Roger, Brännström Thomas, Broholm Helle, Christensen Helle Collatz, Ahlbom Anders, Auvinen Anssi, Feychting Maria, Lönn Stefan, Kiuru Anne, Swerdlow Anthony, Schoemaker Minouk, Roos Göran, Malmer Beatrice
Abstract excerpt
The human telomerase reverse transcriptase (hTERT) gene is upregulated in a majority of malignant tumours. A variable tandem repeat, MNS16A, has been reported to be of functional significance for hTERT expression. Published data on the clinical relevance of MNS16A variants in brain tumours have been contradictory. The present population-based study in the Nordic countries and the United Kingdom evaluated...
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