Article
Sphingolipids in the root play an important role in regulating the leaf ionome in Arabidopsis thaliana.
The Plant cell - 1 Mar 2011
Chao Dai-Yin, Gable Kenneth, Chen Ming, Baxter Ivan, Dietrich Charles R, Cahoon Edgar B, Guerinot Mary Lou, Lahner Brett, Lü Shiyou, Markham Jennifer E, Morrissey Joe, Han Gongshe, Gupta Sita D, Harmon Jeffrey M, Jaworski Jan G, Dunn Teresa M, Salt David E
Abstract excerpt
Sphingolipid synthesis is initiated by condensation of Ser with palmitoyl-CoA producing 3-ketodihydrosphinganine (3-KDS), which is reduced by a 3-KDS reductase to dihydrosphinganine. Ser palmitoyltransferase is essential for plant viability. Arabidopsis thaliana contains two genes (At3g06060/TSC10A and At5g19200/TSC10B) encoding proteins with significant similarity to the yeast 3-KDS reductase, Tsc10p....
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