Article
Associations of PRKN-PACRG SNPs and G × G and G × E interactions with the risk of hyperlipidaemia.
Scientific reports - 3 Aug 2020
Zheng Peng-Fei, Yin Rui-Xing, Wei Bi-Liu, Liu Chun-Xiao, Deng Guo-Xiong, Guan Yao-Zong
Abstract excerpt
This research aimed to assess the associations of 7 parkin RBR E3 ubiquitin protein ligase (PRKN) and 4 parkin coregulated gene (PACRG) single-nucleotide polymorphisms (SNPs), their haplotypes, gene-gene (G × G) and gene-environment (G × E) interactions with hyperlipidaemia in the Chinese Maonan minority. The genotypes of the 11 SNPs in 912 normal and 736 hyperlipidaemic subjects were detected with...
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