Article
Association of five SNPs at the PARK16 locus as a susceptibility locus with Parkinson's disease for forensic application.
Fa yi xue za zhi - 1 Jun 2013
Cui Hong-Gang, Tian Xiao-Fei, Luo Xiao-Guang, Li Feng-Rui, Zhu Lan-Hui, Zhou Yi-Shu, Ren Yan, Pang Hao
Abstract excerpt
To investigate the association of five SNPs (rs823083, rs708723, rs4951261, rs823076 and rs16856110) at the PARK16 locus with Parkinson's disease (PD), and to potentiate its forensic application. The genomic DNAs of 215 PD patients and 212 matched controls from the northern Han Chinese population were amplified in two independent PCR systems and subsequently genotyped by digestion with the three endonucleases...