Article
Diversity in junctional sequences associated with the common human V gamma 9 and V delta 2 gene segments in normal blood and lung compared with the limited diversity in a granulomatous disease.
The Journal of experimental medicine - 1 Jul 1990
Tamura N, Holroyd K J, Banks T, Kirby M, Okayama H, Crystal R G
Abstract excerpt
The T cell receptor (TCR) junctional regions (N regions) of the common human V gamma 9 and V delta 2 gene segments were sequenced from the blood and lung of normal individuals (195 transcripts) and a group of individuals with sarcoidosis (220 transcripts), a granulomatous disease in which increas...
Topics
- Adult
- Antibodies, Monoclonal
- Base Sequence
- DNA
- Female
- Flow Cytometry
- Gene Expression
- Genetic Variation
- Humans
- Lung
- Male
- Molecular Sequence Data
- Phenotype
- RNA, Messenger
- Receptors, Antigen, T-Cell