Article
Emergence of teicoplanin resistance during therapy of Staphylococcus aureus endocarditis.
The Journal of infectious diseases - 1 Jul 1990
Kaatz G W, Seo S M, Dorman N J, Lerner S A
Abstract excerpt
Serial isolates of Staphylococcus aureus showing two- to eightfold increases in teicoplanin minimum inhibitory concentrations (MICs) and twofold or less increases in MICs of other glycopeptides were recovered from the blood of a patient with endocarditis in whom drug therapy was unsuccessful. Comparable resistance emerged during teicoplanin treatment of rabbits with endocarditis caused by the original susceptible...
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