Article
Genetic variability of cytomegalovirus glycoprotein O in hematopoietic stem cell transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society - 1 Jun 2011
Roubalova K, Strunecky O, Vitek A, Zufanova S, Prochazka B
Abstract excerpt
UNLABELLED: Genetic variation of cytomegalovirus (CMV) strains can correlate with their pathogenicity for immunocompromised patients. Glycoprotein O (gO), together with glycoprotein L and glycoprotein H, mediate the fusion of the viral envelope with the cell membrane and promotes virus penetration, envelopment, and release. The variability of gO might play a role in CMV cell tropism. The goal was a retrospective...
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