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Article

Analysis and clinical correlation of genetic variation in cytomegalovirus.

Transplant infectious disease : an official journal of the Transplantation Society - 1 Apr 2012

Lisboa L F, Tong Y, Kumar D, Pang X L, Asberg A, Hartmann A, Rollag H, Jardine A G, Pescovitz M D, Humar A

Abstract excerpt

BACKGROUND: Cytomegalovirus (CMV) displays genetic polymorphisms in multiple genes, which may result in important virulence differences. Glycoprotein N (gN) and immediate early 1 (IE1) are key viral genes and immune targets. We aimed to characterize the molecular epidemiology of gN and IE1 genotypes in organ transplant patients with CMV disease in the context of clinical and virologic endpoints. METHODS: A total...

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Identifiers

PMID: 22093996
DOI: 10.1111/j.1399-3062.2011.00685.x

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