Article
Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells.
PloS one - 2 Mar 2011
Yuan Shauna H, Martin Jody, Elia Jeanne, Flippin Jessica, Paramban Rosanto I, Hefferan Mike P, Vidal Jason G, Mu Yangling, Killian Rhiannon L, Israel Mason A, Emre Nil, Marsala Silvia, Marsala Martin, Gage Fred H, Goldstein Lawrence S B, Carson Christian T
Abstract excerpt
BACKGROUND: Neural induction of human pluripotent stem cells often yields heterogeneous cell populations that can hamper quantitative and comparative analyses. There is a need for improved differentiation and enrichment procedures that generate highly pure populations of neural stem cells (NSC), glia and neurons. One way to address this problem is to identify cell-surface signatures that enable the isolation of...
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