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Article

A complex double deletion in LMNA underlies progressive cardiac conduction disease, atrial arrhythmias, and sudden death.

Circulation. Cardiovascular genetics - 1 Jun 2011

Marsman Roos F, Bardai Abdennasser, Postma Alex V, Res Jan C J, Koopmann Tamara T, Beekman Leander, van der Wal Allard C, Pinto Yigal M, Lekanne Deprez Ronald H, Wilde Arthur A M, Jordaens Luc J, Bezzina Connie R

Abstract excerpt

BACKGROUND: Cardiac conduction disease is a clinically and genetically heterogeneous disorder characterized by defects in electrical impulse generation and conduction and is associated with sudden cardiac death. METHODS AND RESULTS: We studied a 4-generation family with autosomal dominant progressive cardiac conduction disease, including atrioventricular conduction block and sinus bradycardia, atrial arrhythmias,...

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Share to Arrhythmias, Cardiac
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Death, Sudden, Cardiac

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Share to Heart Conduction System

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Source

Identifiers

PMID: 21406687
DOI: 10.1161/CIRCGENETICS.110.959221

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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