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Electroporation-Mediated Transfer of <i>SOX Trio</i> Genes ( <i>SOX-5, SOX-6</i> , and <i>SOX-9</i> ) to Enhance the Chondrogenesis of Mesenchymal Stem Cells

14 Mar 2011

Abstract excerpt

The purpose of this study was to test the hypothesis that the SOX trio genes (SOX-5, SOX-6, and SOX-9) have a lower level of expression during the chondrogenic differentiation of mesenchymal stem cells (MSCs) compared with chondrocytes and that the electroporation-mediated gene transfer of SOX trio promotes chondrogenesis from human MSCs. An in vitro pellet culture was carried out using MSCs or chondrocytes at...

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Identifiers

PMID: 21401405
DOI: 10.1089/scd.2010.0516

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Electroporation-Mediated Transfer of <i>SOX Trio</i> Genes ( <i>SOX-5, SOX-6</i> , and <i>SOX-9</i> ) to Enhance the Chondrogenesis of Mesenchymal Stem CellsPMID 21401405Read ↗

The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.Semantic proximity Read ↗

Brief Report: Importance of SOX8 for In Vitro Chondrogenic Differentiation of Human Mesenchymal Stromal CellsSemantic proximity Read ↗

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