Article
Bayesian semiparametric meta-analysis for genetic association studies.
Genetic epidemiology - 1 Jul 2011
De Iorio Maria, Newcombe Paul J, Tachmazidou Ioanna, Verzilli Claudio J, Whittaker John C
Abstract excerpt
We present a Bayesian semiparametric model for the meta-analysis of candidate gene studies with a binary outcome. Such studies often report results from association tests for different, possibly study-specific and non-overlapping genetic markers in the same genetic region. Meta-analyses of the results at each marker in isolation are seldom appropriate as they ignore the correlation that may exist between markers...
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