The evolutionary dynamics of endogenous retroviruses.

doi:10.1016/j.tim.2005.08.004

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Article

The evolutionary dynamics of endogenous retroviruses.

Trends in microbiology - 1 Oct 2005

Katzourakis Aris, Rambaut Andrew, Pybus Oliver G

Abstract excerpt

Endogenous retroviruses (ERVs) are vertically transmitted intragenomic elements derived from integrated retroviruses. ERVs can proliferate within the genome of their host until they either acquire inactivating mutations or are lost by recombinational deletion. We present a model that unifies current knowledge of ERV biology into a single evolutionary framework. The model predicts the possible long-term outcomes...

Topics

Endogenous Retroviruses
Evolution, Molecular
Genetic Variation
Models, Biological

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Open in PubMed

Identifiers

PMID: 16109487
DOI: 10.1016/j.tim.2005.08.004

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