Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants.

Genetics - 1 May 2011

Zhuang Jimmy J, Hunter Craig P

Abstract excerpt

Gene knockdown by RNA interference (RNAi) in Caenorhabditis elegans is readily achieved by feeding bacteria expressing double-stranded RNA (dsRNA). Enhanced RNAi (Eri) mutants facilitate RNAi due to their hypersensitivity to dsRNA. Here, we compare eight Eri mutants for sensitivity to ingested dsRNA, targeting a variety of tissue-specific genes.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Genetic Testing
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Organ Specificity

Share to Phenotype

Share to RNA, Double-Stranded

Share to RNA Interference

Source

Open in PubMed Open full text

Identifiers

PMID: 21385728
DOI: 10.1534/genetics.111.127209
PMCID: PMC3120140

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants.PMID 21385728Read ↗

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans.Semantic proximity Read ↗

New strains for tissue-specific RNAi studies in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.Semantic proximity Read ↗

A pre- and co-knockdown of RNAseT enzyme, Eri-1, enhances the efficiency of RNAi induced gene silencing in Caenorhabditis elegans.Semantic proximity Read ↗

High-throughput reverse genetics: RNAi screens in Caenorhabditis elegans.Semantic proximity Read ↗

C. elegans rrf-1 mutations maintain RNAi efficiency in the soma in addition to the germline.Semantic proximity Read ↗

Uncover genetic interactions in Caenorhabditis elegans by RNA interference.Semantic proximity Read ↗

An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans.Semantic proximity Read ↗

Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans.Semantic proximity Read ↗

Construction of a germline-specific RNAi tool in <i>C. elegans</i>Semantic proximity Read ↗

Establishment of a tissue-specific RNAi system in C. elegans.Semantic proximity Read ↗

Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.